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antibody-coated target

См. также в других словарях:

  • antibody-dependent cell-mediated cytotoxicity — (ADCC) The killing of antibody coated target cells by cells with Fc receptors that recognize the Fc region of the bound antibody. Most ADCC is mediated by NK cells that have the Fc receptor or CD16 on their surface …   Dictionary of microbiology

  • antibody — /an ti bod ee/, n., pl. antibodies. 1. any of numerous Y shaped protein molecules produced by B cells as a primary immune defense, each molecule and its clones having a unique binding site that can combine with the complementary site of a foreign …   Universalium

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

  • Antibody-dependent cell-mediated cytotoxicity — An immune response in which antibody, by coating target cells, makes them vulnerable to attack by immune cells. Antibody dependent cell mediated cytotoxicity is commonly (and blissfully) abbreviated ADCC. * * * (ADCC), antibody dependent cellular …   Medical dictionary

  • antibody — An immunoglobulin molecule produced by B lymphoid cells with a specific amino acid sequence evoked in humans or other animals by an antigen (immunogen). These molecules are characterized by reacting specifically with the antigen in some… …   Medical dictionary

  • killer cells — (= K cells) (1) Mammalian cells which can lyse antibody coated target cells. They have a receptor for the Fc portion of IgG, and are probably of the mononuclear phagocyte lineage, though some may be lymphocytes. Not to be confused with cytotoxic… …   Dictionary of molecular biology

  • Immunoprecipitation — (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein. This process can be used to isolate and concentrate a particular protein from a sample containing many… …   Wikipedia

  • Fc receptor — An Fc receptor is a protein found on the surface of certain cells including natural killer cells, macrophages, neutrophils, and mast cells that contribute to the protective functions of the immune system.Its name is derived from its binding… …   Wikipedia

  • Cell — The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane. Each cell in the human body there are 100 trillion cells in each of us contains the entire… …   Medical dictionary

  • Ricin — (pronEng|ˈraɪ sɨn) is a protein toxin that is extracted from the castor bean ( Ricinus communis ).The U.S. Centers for Disease Control (CDC) gives a possible minimum figure of 500 micrograms (about the size of a grain of salt) Fact|date=May 2008… …   Wikipedia

  • Pathatrix — is a unique high volume recirculating immuno magnetic capture system for the detection of pathogens in food and environmental samples. Pathatrix was used during the E. coli O157 outbreak in 2006 that was linked to contaminated spinach. The use of …   Wikipedia

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